Histopathology / Cytopathology / Hematopathology / PLA Home Page
Test Code: 3333
Method: Polymerase chain reaction (PCR)-Qualitative
Specimen requirements: SurePath: 1.0 mL (0.50 mL) minimum.
Collection and transport: SurePath: Store and ship at ambient temperature up to 28 days. ThinPrep: Store and ship at ambient temperature up to 3 months/ 90 days.
Causes for rejection: SurePath: Less than 0.50 mL and/ or more
than 28 days.
Reference range: Not Detected.
TAT: 1-5 days.
CPT code: 8749, Chlamydia trachomatis amplified probe technique.
Clinical significance: Chlamydia trachomatis infections are among the most common sexually transmitted bacterial infections in the United States with approximately 4 million new cases occurring annually. The speed and enhanced sensitivity of the Roche amplified DNA probe methodology enables early, accurate detection of Chlamydia trachomatis, resulting in timely administration of therapy. Several publications involving multiple centers have demonstrated a sensitivity of greater than 96.6% in the detection of Chlamydia and a specificity greater that 99%.