Histopathology / Cytopathology / Hematopathology / PLA Home Page
Test indication: For detection and characterization of endoscopically visible gastrointestinal lesions; for the identification of some microbiologic pathogens (e.g. herpes, CMV, and Candida, etc.).
Specimen required: Endoscopically obtained washing (preferably at least 10 mL) of the region of the suspected lesion.
Supplies: Standard endoscopy equipment. 120 mL clean plastic specimen container(s). Fixative (either CytoRich Red cytology preservative or 50% ethanol), biohazard transport bag.
Collection procedure: Instruct the patient to fast overnight or for
a minimum of six hours prior to the procedure. Lavage the area
of interest with physiologic solution using standard endoscopy
technique. Aspirate the solution and place in a clean specimen
container. Label the container with the patients first
and last name, date of birth and specimen source. Submit the
specimen and the completed Cytology
test request form to the Cytopathology Laboratory.
Transport: Each specimen should be placed in a clearly labeled container that is leak proof. Place specimen inside a biohazard transport bag. Paper requisition(s) that accompany the specimen or slides in fixative should be placed in the outside pocket of the biohazard bag to avoid exposure to any leakage of fixative.
Causes for rejection: Incomplete patient requisitions, unlabeled/incorrectly labeled specimen, frozen specimen, incorrect test ordered for specimen, specimen in incorrect or expired fixative, specimen from unauthorized person.
Specimen Stability: 4 hours fresh refrigerated (4°C or 39°F), all GI specimens tend to deteriorate rapidly in the fresh statedue to enzymatic activity endogenous to the GI tract.
Reference interval: By report.
CPT code(s): 88108 Concentration and interpretation, 88112 Selective cellular enhancement with interpretation. Additional CPT codes may apply if special studies are required.