Histopathology / Cytopathology / Hematopathology / PLA Home Page
The Vysis Urovysion®
Method: Fluorescence in situ hybridization (FISH).
Specimen requirements: 50 ml (minimum). Note: First voided urine or bladder wash increases specimen cellularity.
Specimen type: Voided urine, bladder wash catheter urine, renal wash, ileal conduit, post cystotomy wash.
Collection and transport: Patients should be well hydrated prior to collection.
Refrigerate specimen until preserved. Add an equal amount of
50% ethanol or CytoRich Red cytology preservative to 50-100
ml urine or washing/conduit specimen collected. Store at room
temperature once preserved.
Interpretative data: The Vysis Urovysion® Bladder Cancer FISH assay
should be used as a noninvasive method to monitor urothelial
carcinoma. These findings should be interpreted in association
with other clinical and pathological findings. The Vysis®
ICD9 code: Required on all patient requisitions.